香港科技大學
2009-2010
年報
48
研究與發展
RESEARCH AND DEVELOPMENT
HKUST 2009-2010 Annual Report
49
pathophysiological mechanisms underlying specific
neuromuscular disorders, and will be invaluable in
the design of novel therapeutic agents. Their study
was published in the January 2010 issue of
Neuron
,
the most prestigious journal in neuroscience.
•
Prof Mingjie Zhang, Department of Biochemistry, and
his team of researchers have made a breakthrough
discovery on how motor proteins like myosin VI
behave. As the myosin VI protein is essential to the
well being of cells in general and its mutation is
known to cause hereditary blindness and deafness
as well as cancer, this discovery is expected to have
a far reaching and fundamental impact on medical
science.
•
HKUST will spearhead a Hong Kong team to take
part in the largest ever International Cancer Genome
Consortium (ICGC) which will decode genomes
from 25,000 cancer samples related to 50 types
and subtypes of cancer to create a freely available
database with data that could be used immediately
by medical researchers around the world to help
prevent, detect, diagnose and treat cancer. The
Consortium published an article in
Nature
in April
2010. Prof Hannah H Xue of the Department of
Biochemistry, along with Prof Matthew Yuen, Acting
Vice-President for Research and Development, are
taking part in the Consortium.
•
Prof Lionel M Ni and Prof Qian Zhang, Department
of Computer Science and Engineering, have
developed a wireless communication system for
Boeing’s commercial planes to facilitate onboard
entertainment, as well as communication among
maintenance technicians. It focuses on the problem
of seamless connectivity among different networks
used by aircraft line maintenance technicians at
airports. This aims to enable efficient wireless
communication to reduce the maintenance period
and prevent disruptions to flight schedules.
•
Prof Qiang Yang, Department of Computer Science
and Engineering, is working on two projects with
Microsoft Research Asia one on ehealth technology
and sensor nets, namely “mCARE: Mobile cloud for
activity recognition for ehealth” and “Co-mining:
Bridging the physical world and the virtual world”.
He also has an RGC NSFC supported project on
“Heterogeneous transfer learning with applications
to the web”.
•
Prof Arthur Lau, Dr NT Lau and Prof Chak K Chan,
the Division of Environment, used the Mobile Real-
time Air Monitoring Platform (MAP) to study street
level air quality in the 18 districts of Hong Kong. The
Division of Environment has also received a HK$6.5
million grant from the Environmental Conservation
Fund of HKSAR to build a particulate matter supersite
to study a wide range of air pollution problems
based on real time characterization of the pollutants.
•
The School of Business and Management has
achieved consistently high international rankings. Its
research performance in marketing was placed third
in rankings by the University of Texas at Dallas (UTD)
based on publications in the top three marketing
journals. Its research performance in management
has also been ranked third by UTD, based on
publications in the five top management journals.
Gordon Research Conference
HKUST hosted the 2010 Gordon Research Conference
(GRC) on Molecular and Cellular Neurobiology which
was the first and only Gordon Research Conference held
in Asia. The prestigious conference played an important
role in promoting interactions between US and Asia-
based neuroscientists.
First State Key Laboratory
The Ministry of Science and Technology of China has
approved the establishment of the State Key Laboratory
(SKL) of Molecular Neuroscience at HKUST to build
on our existing foundation of excellence in molecular
neuroscience. The national standing granted to this
laboratory signifies recognition from the Central
Government of our academic excellence in neuroscience
research. Prof Nancy Ip, Chair Professor of Biochemistry,
has been appointed the founding Director of the SKL.
The laboratory will serve as the foundation for world-
class research, attracting and nurturing outstanding
researchers, as well as providing a solid platform for
scholarly exchanges.
•
電子及計算機工程系的劉紀美教授與學生研發出應用
納米光電子技術的半導體微顯示器件。在她的帶領
下，科大光電科技中心發明了矽基板LED微顯示技術
(LEDoS) - 音譯為「領導技術」。LEDoS運用倒裝晶片技
術在矽基有源矩陣基板上封裝高解像及高亮度的LED
微陣列。LEDoS 技術具有光明的應用前景，例如移動
電子產品的顯示器、電子書、攜帶式微型投影機、生
物感測器陣列及可編程光源。
•
生物化學系葉玉如教授的研究取得重大突破，識別出
運動機能正常運作不可或缺的訊號蛋白。研究小組曾
作多方面嘗試，證實缺乏細胞骨架調節蛋白ephexin1
的老鼠會肌肉乏力，神經肌肉接合點的發育亦存在嚴
重缺陷。這些令人振奮的發現為了解特定神經肌肉失
調症的病理生理機制提供了重要線索，對於研製新型
治療藥物的價值更是不可估量。他們的研究已於2010
年1月發表於神經科學界最權威的期刊《Neuron》。
•
生物化學系張明傑教授與他的研究團隊多年來進行人
體細胞內「肌球蛋白6」運動模式的研究，最近取得重
大突破。「肌球蛋白6」是維持細胞健康的重要元素，
而它的突變會導致遺傳性失明和失聰，甚至癌症。因
此，這項發現對醫療科學的發展影響深遠。
•
科大將組織香港團隊參與歷來最大的國際腫瘤基因組
聯盟，破解來自50種癌症共25,000個腫瘤樣本的基因
組，並建立一個全球醫學研究人員均可即時及自由使
用的數據庫，協助預防、發現、診斷及治療癌症。該
聯盟於2010年4月在《自然》發表了學術文章，參與者
包括生物化學系薛紅教授與署理副校長（研究及發展）
袁銘輝教授。
•
計算機科學及工程學系倪明選教授及張黔教授為波音
商務客機開發無線通訊系統，以提升機上娛樂和維修
技術員之間的通訊。該系統著重解決機場航線維修技
術員所用不同網絡間的無縫連接問題，旨在提高無線
通訊效率以縮短維修時間，避免阻礙航班升降。
•
計算機科學及工程學系楊強教授參與微軟亞洲研究院
兩個有關電子健康科技及傳感器網絡的項目，分別為
「mCARE：電子健康活動識別的流動雲（Mobile cloud
for activity recognition for the ehealth）」及「共同發
掘：連接現實世界與虛擬世界（Bridging the physical
world and the virtual world）」。他亦獲研資局及國家
自然科學基金委員會聯合資助的計劃「異類轉移學習
及 網 絡 應 用（Heterogeneous transfer learning with
applications to the web）」。
•
環境學部劉培生教授、劉毅廷博士及陳澤強教授利用
「大氣監測走航平台 」研究全港18區的路邊空氣質素。
環境學部亦獲香港特別行政區環境及自然保育基金撥
款650萬港元建造微粒監測站，根據污染物的實時描繪
研究各種空氣污染問題。
•
工商管理學院繼續高踞國際排行榜前列位置。按照德
克薩斯大學達拉斯分校的排名，工商管理學院的市場
研究表現及管理研究表現雙雙晉身全球三甲之列。相
關排名評分是分別根據院校在三份最具權威性的市場
學期刊及五份最具權威性的管理學期刊上所發表的
文章。
