香港科技大學2005-2006年報
34
研究與發展
Research & Development
生物化學系
夏軍博士
與其研究小組發現，染色體蛋白（PICK1）
透過一個最新認定的BAR 領域，直接連接主要是磷酸肌醇的脂
質。他們亦首次發現蛋白－脂質活躍地互動，對染色體蛋白的
發現極為重要。
Dr Jun Xia
, Department of Biochemistry, and his research
team discovered that a synaptic protein, PICK1, directly binds
to lipids, mainly phosphoinositides, via a newly identified BAR
domain. They also found, for the first time, that a dynamic
protein-lipid interaction was important for targeting of synaptic
protein.
以下是在2005-06年，科大取得研究成果的部份重點項目：
The following highlights are among the University’s research successes in 2005-06:
科大的中文語言中心與位於西雅圖的華盛頓大學的Li Fang-Kuei Society中文語言學會，合辦了一個新的供同儕評審而名為Bulletin of
Chinese Linguistics的國際期刊，目的是對中國及鄰近地區常用的語言，加深理論層面的認識。這是全球首本專門探討中文語言歷史
的學術期刊。
HKUST’s Center for Chinese Linguistics launched a new peer-reviewed international journal, Bulletin of Chinese Linguistics,
in conjunction with the Li Fang-Kuei Society for Chinese Linguistics based at the University of Washington in Seattle. It is
dedicated to advancing theoretical understanding of languages spoken in China and neighboring regions. This is the first
academic journal world-wide devoted primarily to Chinese historical linguistics.
夏軍博士
Dr Jun Xia
生物化學系
林聖彩博士
與其研究小組發現，洋蟲膠（Axin）在
TGF-beta訊號路線裡，是一個主要的骨幹蛋白。結合他們之
前的研究，這個嶄新的發現，確立了洋蟲膠以多種方式抑制
腫瘤活動。
Dr Shengcai Lin
, Department of Biochemistry, and his research
group found that Axin serves as a major scaffolding protein in
the TGF-beta signaling pathway. Coupled with their previous
research, this finding establishes that Axin exerts tumor
suppression activity by multiple means.
林聖彩博士
Dr Shengcai Lin
生物學系
張東才教授
與化學工程學系
羅茜博士
，研製出一個
分子生物感應器，可快速偵測會導致癌細胞內程式細胞死亡
的化學混合物，並已在美國及中國取得專利。
Professor Donald Chang
, Department of Biology, and
Dr
Kathy Luo
, Department of Chemical Engineering, have
received US and Chinese patents for a molecular biosensor
to rapidly screen chemical compounds that can trigger
programed cell death in cancer cells.
張東才教授
Professor Donald C Chang
羅茜博士
Dr Kathy Qian Luo
Research Highlights
In addition to the five high-impact areas, HKUST carries out research in
many other fields within and across its four Schools. The quality of such
work is reflected in the University’s on-going success in the annual
internationally peer-reviewed Research Grants Council Competitive
Earmarked Research Grant (CERG) allocation. In results announced in
June 2006, HKUST remained Hong Kong’s leading university in terms
of research projects funded under this allocation.
研究重點
除了五個重點研究領域外，科大亦進行四個學院
內跨學科及跨學院的研究。科大每年都取得香港
研究資助局角逐研究用途補助金的研究撥款，反
映我們卓越的科研成績，事實上，這些研究項目
經均經過國際同儕的嚴格評審。在 2006年6月
公佈的報告中，以研究項目所獲得補助金的成功
率，科大名列香港各高等教育院校之冠。
